Research Journey

My Cancer Research Journey as a Story

By Ramadhani Chambuso

In clinical medicine, researchers believe that HIV/HPV co-infected women progress relatively rapidly to invasive cervical cancer.

But then, I thought that may be too general because others do not progress to the invasive disease regardless of their CD4 T cell counts or Anti-Retroviral drug use.

Therefore, what I did, was to find out if host immunity and molecular genetic variations with HIV/HPV co-infection may influence early cervical cancer development. Interestingly, I have discovered that specific immune genes in combination with HIV/HPV co-infection may influence cervical cancer development in South African Women.

Conclusively, these results enlighten our insight to the disease development, add new knowledge to the existing theories in Clinical Oncology and may change the screening and management of the disease to focus or target more on individualized molecular genetic variations for cervical carcinogenesis.

3 thoughts on “Research Journey”

  1. Hi Ramadhani,
    I am just curious. Did you have controls, say those without any HPV/HIV co-infections and those with only one of these viruses?

Leave a Reply to Ramadhani Cancel reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>